The Fluid Mosaic Model - according to this model, the membrane is a bilayer of phospholipids with proteins at random inserted in and on the bilayer. Phospholipid Structure Glycerol backbone (C3) Fatty acids are esterified to two of the carbon atoms. One fatty acid is usually saturated, the other one is unsaturated The unsaturated fatty acid is "kinked" which prevents the phospholipids from packing too tightly and for this reason, the membrane remains more fluid at cool temperatures. In fact, the degree of unsaturation in the fatty acids in phospholipids is inversely correlated with temperature. Another way that membranes remain reasonably fluid is by incorporating cholesterol and other sterols. These hydrophobic molecules also break up the tight aggregation of phospholipids that would occur at cool temperatures. The fatty acids are hydrophobic (non-polar). . Phosphate - is esterified to the third carbon. A polar group is attached to the phosphate. Choline is a common polar group. The unifying features of the polar groups are: (a) they have an electrical charge and (b)......

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