ANTIBIOTIC RESISTANCE Disease-causing microbes that have become resistant to drug therapy are an increasing public health problem. Unless antibiotic resistance problems are detected as they emerge, and actions are taken to contain them, the world could be faced with previously treatable diseases that have again become untreatable, as in the days before antibiotics were developed. In short, antimicrobial resistance is driving up health care costs, increasing the severity of disease, and increasing the death rates from certain infections. AR will always be with us. There is no way to stop or avoid that problem. The challenge before us is to transform this increasingly urgent threat into a manageable problem. Over the past ten years, the Institute of Medicine, the American Society for Microbiology, World Health Organization, the Congressional Office of Technology Assessment, and the General Accounting Office have provided recommendations and options for government action to address the dangers posed by AR. The experts agree that we need to improve surveillance for emerging AR proble......

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