EXECUTIVE SUMMARY  This is a paper analyzing the key risks that Major Pharmaceutical firms face in the 3-year timeframe with major patent expirations due in 2013 and offers a framework for addressing those risks. Our representative firms would be Johnson & Johnson, Bristol Myers, Pfizer, Merck, Novartis, AstraZeneca, Eli Lilly, Glaxo and firms of similar size and clout. We believe that there are significant cash flow and drug pipeline risks for firms in this genre and we offer some suggestions to mitigate or hedge risks by acquiring smaller companies with promising drugs and also changing business strategy to address the threat from generics. We also discuss the legal and regulatory risks of these firms as they have some special challenges compared to other businesses. LEGAL/REGULATORY RISKS The Legal and Regulatory nature of the Pharma business is probably more complex than or just as complex as any other business. * Drug safety and liability issues: Just this week (Feb 22,2010 - US News and World Report), Glaxo a big pharma took a big sales and PR h......

Word Count: 2773
Page Count: 11 (250 words a page / double spaced)

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